Sr Principal Scientist

• State of the art knowledge of process chemistry, analytical chemistry, scale-up, modern synthetic methodology, including aspects of asymmetric synthesis, green chemistry, catalysis, and physical organic chemistry as it relates to reaction mechanism is expected.
• Contemporary knowledge of drug development, the pharmaceutical industry, and fundamental principles of process development from a laboratory and manufacturing perspective.
• Strong track record of managing integrated synthetic chemistry development laboratories with 15-30 process chemists and analytical chemists.
• Strong track record of successful delivery of projects, using sound scientific analysis and judgment to advance programs.
• Good interpersonal skills
• Experience of leading and developing teams, mentoring and directing other colleagues.
• Excellent oral and written communication skills, including the ability to maintain an accurate scientific notebook, and draft concise emails, written reports, publications, synthesis information packages and related documents
• Rational, innovative and creative approach to problem solving.
• Capable of leading and planning the scientific direction of multi-discipline projects.

• Lead a group of 15-30 process and analytical chemists at an external partner located in India to deliver phase-appropriate processes, analytical methods and vendor synthetic information packages (VSIPs) for Pfizer’s Drug-Linker portfolio.
• Work with Pfizer and external partner’s EHSS groups to develop and implement best practices for the synthesis, purification and handling of low OEL compounds.
• Use extensive technical knowledge and experience in state-of-the-art organic and process chemistry to personally deliver and lead others in the development of safe, sustainable, robust, cost-efficient and phase-appropriate process that are aligned with internal business needs.

• Develop, refine, and maintain productivity metrics of FTEs for resource allocation discussions with key internal stakeholders.
• Develop strategic plans to drive improvement in lab capabilities (process chemistry and analytical chemistry) and enhance productivity.
• Develop secure and robust data sharing infrastructure between Pfizer and external partners in collaboration with IT and functional areas
• Set up business workflows to streamline material shipment and logistics
• Build a safe, inclusive, and innovative culture within the chemistry labs.
• Work collaboratively and effectively, building and leading high performing teams

• Ensure accurate and timely documentation of experimental work, and clear and concise presentation of work to stakeholders both internally and externally.
• Develop a strong relationship with external partner management, with open and effective communication and active listening (inc. sharing of plans, co-ordination of resources, alignment of priorities).
• Build a strong interface and network with Pfizer’s Chemical Process and Analytical Development group (Global Chemical Research and Development) and keep up to date with synthetic and technology advancements.
• Look for opportunities to align, share and implement best practices across sites.

• Master’s degree in Chemistry, Chemical Engineering or a related field and 15+ years of experience in process chemistry research and development towards New Chemical Entities (APIs) or fine chemicals

or

• PhD in Organic Chemistry, API, Chemical synthesis or a related field with 8+ years of experience in process chemistry research and development towards New Chemical Entities (APIs) or fine chemicals
• Experience in leading cross-functional teams is a plus.

PHYSICAL/MENTAL REQUIREMENTS

N/A

NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS

• Due to the need to support global operations, the employee may be required to attend teleconference meetings that are outside of core work hours in IST.
• Local business travel to support vendor oversight activities <10%. of work time.

  
Work Location Assignment: On Premise

Pfizer is an equal opportunity employer and complies with all applicable equal employment opportunity legislation in each jurisdiction in which it operates.

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Experience Level

Senior Level