Program Manager

PLM Program/Operation Lead

What if the work you did every day could impact the lives of people you know? Or all of humanity?At Illumina, we are expanding access to genomic technology to realize health equity for billions of people around the world. Our efforts enable life-changing discoveries that are transforming human health through the early detection and diagnosis of diseases and new treatment options for patients.Working at Illumina means being part of something bigger than yourself. Every person, in every role, has the opportunity to make a difference. Surrounded by extraordinary people, inspiring leaders, and world changing projects, you will do more and become more than you ever thought possible.

Job Summary

The PLM Program / Operations Lead (P04) is responsible for supporting PLM strategy and driving operational execution across complex, cross‑functional PLM initiatives. This role partners closely with PLM Strategy & Excellence, PLM Operations and key stakeholders to ensure seamless delivery and effective execution of PLM Strategy & Roadmap while providing accurate forecasting, and strong program governance. The position operates with a high level of autonomy and serves as a critical link between strategy and execution.

Key Responsibilities

• Support PLM leadership by translating strategic priorities into actionable plans, programs, and milestones
• Partner with PLM Strategy & Excellence and PLM Operations to deliver PLM initiatives on time, within scope, and with high quality
• Serves as the gatekeeper of End-to-End PLM Business Process Maps, supporting narratives, value stream analysis and relevant Roadmap artefacts
• Champions and evolves PLM Solution Architecture that involves Business Process Architecture, Data Architecture, Master Data Management & Data Governance Develop and maintain forecasts for program delivery, capacity, and execution risks
• Lead program management and Governance activities, including milestone tracking, dependency management, risk and issue tracking, and KPI reporting
• Establish and maintain program governance, reporting cadence, and execution discipline
• Collaborate with Engineering, Quality, Supply Chain, Manufacturing, IT, and Business teams to ensure alignment and resolve execution challenges
• Act as a primary point of contact for stakeholders, ensuring clear, timely, and effective communication
• Prepare executive‑ready status updates, dashboards, and reports to support leadership decision‑making

Required Qualifications

• Bachelor’s degree in engineering, Business, Operations, or Life science graduation
• 8+ years of experience in PLM operations, Master Data Operations, program management, or business operations
• Strong experience working cross‑functionally to drive execution and deliver results
• Demonstrated ability to perform business process modeling, solution architecture, Data Architecture, deviation analysis, forecasting, and risk management
• Proven program management skills with the ability to manage multiple initiatives simultaneously
• Excellent written and verbal communication skills, including executive‑level communication
• Ability to work independently, manage ambiguity, and exercise sound judgment

Preferred Qualifications

• Experience in PLM systems and regulated environments (e.g., MedTech, Pharma)
• Familiarity with PLM governance models, KPIs, and operational metrics
• Experience supporting global teams and stakeholders
• Prefer experience with PLM Tools (e.g., Siemens Teamcenter, Agile PLM, SAP PLM), SAP S/4 PLM etc.
• Agentic AI and LLM applications in PLM ecosystem e.g., SAP, Signavio, LIMS, and Camstar

We are a company deeply rooted in belonging, promoting an inclusive environment where employees feel valued and empowered to contribute to our mission. Built on a strong foundation, Illumina has always prioritized openness, collaboration, and seeking alternative perspectives to propel innovation in genomics. We are proud to confirm a zero-net gap in pay, regardless of gender, ethnicity, or race. We also have several Employee Resource Groups (ERG) that deliver career development experiences, increase cultural awareness, and offer opportunities to engage in social responsibility. We are proud to be an equal opportunity employer committed to providing employment opportunity regardless of sex, race, creed, color, gender, religion, marital status, domestic partner status, age, national origin or ancestry, physical or mental disability, medical condition, sexual orientation, pregnancy, military or veteran status, citizenship status, and genetic information. Illumina conducts background checks on applicants for whom a conditional offer of employment has been made. Qualified applicants with arrest or conviction records will be considered for employment in accordance with applicable local, state, and federal laws. Background check results may potentially result in the withdrawal of a conditional offer of employment. The background check process and any decisions made as a result shall be made in accordance with all applicable local, state, and federal laws. Illumina prohibits the use of generative artificial intelligence (AI) in the application and interview process. If you require accommodation to complete the application or interview process, please contact accommodations@illumina.com. To learn more, visit: https://www.dol.gov/ofccp/regs/compliance/posters/pdf/eeopost.pdf. The position will be posted until a final candidate is selected or the requisition has a sufficient number of qualified applicants. This role is not eligible for visa sponsorship.

Experience Level

Senior Level