Principal Cloud Infrastructure Engineer
Syneos HealthJob Description
Principal Engineer
Principal EngineerSyneos Health® is a leading fully integrated biopharmaceutical solutions organization built to accelerate customer success. We translate unique clinical, medical affairs and commercial insights into outcomes to address modern market realities.
Every day we perform better because of how we work together, as one team, each the best at what we do. We bring a wide range of talented experts together across a wide range of business-critical services that support our business. Every role within Corporate is vital to furthering our vision of Shortening the Distance from Lab to Life®.
Discover what our 29,000 employees, across 110 countries already know.
WORK HERE MATTERS EVERYWHERE
Why Syneos Health
- We are passionate about developing our people, through career development and progression; supportive and engaged line management; technical and therapeutic area training; peer recognition and total rewards program.
- We are committed to our Total Self culture – where you can authentically be yourself. Our Total Self culture is what unites us globally, and we are dedicated to taking care of our people.
- We are continuously building the company we all want to work for and our customers want to work with. Why? Because when we bring together diversity of thoughts, backgrounds, cultures, and perspectives – we’re able to create a place where everyone feels like they belong.
Job Responsibilities
Core Responsibilities
Own and evolve standardized infrastructure foundation patterns, configurations, and base images for Windows and Linux platforms.
Build and operate an automation-first provisioning model, ensuring all consumption flows through approved patterns and engineering-defined pipelines (no bespoke/manual builds).
Define and enforce infrastructure-as-code standards, modules, and guardrails to enable repeatable, compliant deployments at scale.
Design and run an “image factory” capability, including automated build, validation, hardening, versioning, and publishing of golden images.
Lead patching, lifecycle, and baseline compliance for foundational infrastructure services, with measurable SLAs/SLOs and audit-ready evidence.
Own capacity management and cloud-native quota modeling (forecasting, trend analysis, thresholds, and lifecycle plans) to ensure predictable supply.
Engineer and maintain network and name services integration, including DNS and Infoblox, ensuring secure and resilient connectivity patterns.
Integrate and operate storage foundations (e.g., NetApp), including standard configurations, access patterns, and lifecycle controls.
Implement identity integration and access patterns that align with enterprise security requirements and platform standards.
Establish controls to eliminate manual variance (policy/validation checks, automated drift detection, and remediation workflows).
Troubleshoot complex infrastructure issues across compute, network, storage, and identity; drive root-cause analysis and continuous improvement through operational rigor.
Apply standards across Azure, GCP, AWS and OCI
Additional Qualifications
Bachelor’s degree in Computer Science, Engineering, or a related field (or equivalent practical experience); advanced degree preferred.
Senior-level experience in infrastructure engineering or solution architecture, with strong emphasis on standardized IaaS foundations and automation in Azure, GCP, AWS and OCI (or comparable cloud environments).
Strong Windows and Linux administration skills, including patching, baseline hardening, and lifecycle management.
Demonstrated expertise with core infrastructure services: networking, SSL, DNS, and Infoblox (or equivalent IPAM/DNS tooling).
Experience with enterprise storage platforms (e.g., NetApp) and standardized storage/access patterns.
Proven ability to integrate identity and access patterns with enterprise directory and security standards.
Hands-on experience building automation and IaC standards (e.g., Terraform/Bicep/ARM), including reusable modules, guardrails, and policy-based controls.
Experience implementing image factory pipelines (build, validation, publishing) and controls that prevent manual variance/drift in builds.
Strong operational rigor: incident/problem management, root-cause analysis, documentation, and measurable service outcomes (SLA/SLO).
Excellent written and verbal communication skills, including the ability to influence stakeholders and align engineering teams to approved patterns and guardrails.
Years of experience required
Minimum of 8 years of Cloud Engineering experience
Get to know Syneos Health
Over the past 5 years, we have worked with 94% of all Novel FDA Approved Drugs, 95% of EMA Authorized Products and over 200 Studies across 73,000 Sites and 675,000+ Trial patients.
No matter what your role is, you’ll take the initiative and challenge the status quo with us in a highly competitive and ever-changing environment. Learn more about Syneos Health.
Additional Information
Tasks, duties, and responsibilities as listed in this job description are not exhaustive. The Company, at its sole discretion and with no prior notice, may assign other tasks, duties, and job responsibilities. Equivalent experience, skills, and/or education will also be considered so qualifications of incumbents may differ from those listed in the Job Description. The Company, at its sole discretion, will determine what constitutes as equivalent to the qualifications described above. Further, nothing contained herein should be construed to create an employment contract. Occasionally, required skills/experiences for jobs are expressed in brief terms. Any language contained herein is intended to fully comply with all obligations imposed by the legislation of each country in which it operates, including the implementation of the EU Equality Directive, in relation to the recruitment and employment of its employees. The Company is committed to compliance with the Americans with Disabilities Act, including the provision of reasonable accommodations, when appropriate, to assist employees or applicants to perform the essential functions of the job.
Experience Level
Senior LevelJob role
Job requirements
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